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ARWRArrowhead Pharmaceuticals, Inc. · Insider ownership research

Arrowhead Pharmaceuticals, Inc. insiders sold $37.3M in the past 12 months. How much of their stake is that?

45% was sold under disclosed trading plans, 48% to cover taxes, 7% with no plan disclosed. The largest seller, Christopher Anzalone (Chief Executive Officer, Director), sold $24.0M.Share-of-stake figures for this company are being verified and will be added when that check is finished. Why

Updated Oct 16, 2026 from SEC filings · covers Oct 17, 2025 to Oct 16, 2026
$2.7M
sold with no plan disclosed, past 12 months
45%
of sales were under disclosed trading plans, past 12 months
10 of 12
officers and directors sold shares, past 12 months
Is this normal? In line with the past 5 years. 10 insiders sold; the average is 10 a year. Year by year
Latest filing: Filed Aug 20 for a sale on Aug 18. Michael Perry sold 12K shares ($1.0M) with no plan disclosed. Filing
SEC ownership filings: 31 filed in the 12 months to Oct 16, 2026; 497 on record since Feb 3, 2004 · See the evidence

What stands out

Michael Perry sold $2.0M of stock with no disclosed trading plan. The filings don't state a reason.Largest such sale, Aug 18, 2026

A share of stake is shown for 0 of the 10 officers and directors who sold. 12 are left out

i
Left out: Christopher Anzalone, Patrick O'Brien, James Hamilton, Michael Perry, Mauro Ferrari, William Waddill, Hongbo Lu, Douglas Ingram, Victoria Vakiener, Adeoye Olukotun, Daniel Apel and Matthew Cohen (share of stake is being verified).
Disclosed company stock is not an insider's whole wealth.

Who sold, and how much of their stake

Officers and directors, past 12 months. Their share of stake is being verified and is not shown yet; amounts and trading plans are below.

Christopher Anzalone
Chief Executive Officer, Director
Not confirmed
Share of stake not shown: share of stake is being verified. Why
$24.0M26% planned, 74% to cover taxes
James Hamilton
Chief Medical Officer
Not confirmed
Share of stake not shown: share of stake is being verified. Why
$3.9MDisclosed plan
Patrick O'Brien
COO
Not confirmed
Share of stake not shown: share of stake is being verified. Why
$3.1MDisclosed plan
Michael Perry
Director
Not confirmed
Share of stake not shown: share of stake is being verified. Why
$2.0MNo plan disclosed
Mauro Ferrari
Director
Not confirmed
Share of stake not shown: share of stake is being verified. Why
$1.0M52% planned 48% no plan disclosed
All 10 sellers

Selling by month

Officers and directors, Oct 2025 to Oct 2026. Each sale is counted once: under a disclosed plan, else to cover taxes, else no plan disclosed.

Disclosed planTo cover taxesNo plan disclosedOne dollar scale for every month; the tallest bar is labeled
OctNov 2025: $493K no plan disclosedNovDec 2025: $7.8M under a disclosed planDec 2025: $17.8M to cover taxesDec 2025: $992K no plan disclosed$26.6MDecJan 2026: $6.5M under a disclosed planJanFebMar 2026: $642K under a disclosed planMarApr 2026: $1.7M under a disclosed planAprMay 2026: $228K under a disclosed planMayJunJulAug 2026: $1.2M no plan disclosedAugSepOct

Recent activity

Past 30 days, Sep 17, 2026 to Oct 16, 2026

No officer or director trades were reported for the past 30 days. The most recent before that:

Aug 18, 20262 directors sold 14K shares ($1.2M) with no plan disclosed.
WhoSharesPrice% of total stakeTotal stake afterTrade dateFiled
Michael Perry
Director
11,600$87.30n/an/aAug 18, 2026Aug 20, 2026
Adeoye Olukotun
Director
2,000$86.96n/an/aAug 18, 2026Aug 20, 2026

Common questions

Is the Arrowhead Pharmaceuticals, Inc. CEO selling stock?

Yes. Christopher Anzalone sold 360K shares ($24.0M) in the past 12 months, 26% of it under a trading plan disclosed in the filings.

Why are Arrowhead Pharmaceuticals, Inc. insiders selling?

Filings rarely give a reason, and we don't guess at one. What they show is how the sales were made: 45% of sales by value ran under 10b5-1 trading plans disclosed in the filings, 48% were to cover taxes and 7% had no disclosed plan. A trading plan schedules sales in advance.

Are any Arrowhead Pharmaceuticals, Inc. insiders buying?

No. Officers and directors reported no purchases in the past 12 months.

The evidence

Who sold10 officers and directors: amount, % of holdings, trading plan
Who soldAmount% of holdingsTrading plan
Christopher Anzalone
Chief Executive Officer, Director
$24.0M
360K shares
Not confirmed
share of stake is being verified. Why
26% under a disclosed plan, 74% to cover taxes
James Hamilton
Chief Medical Officer
$3.9M
60K shares
Not confirmed
share of stake is being verified. Why
Disclosed plan
Patrick O'Brien
COO
$3.1M
49K shares
Not confirmed
share of stake is being verified. Why
Disclosed plan
Michael Perry
Director
$2.0M
28K shares
Not confirmed
share of stake is being verified. Why
No plan disclosed
Mauro Ferrari
Director
$1.0M
16K shares
Not confirmed
share of stake is being verified. Why
52% under a disclosed plan 48% no plan disclosed
Daniel Apel
Chief Financial Officer
$934K
13K shares
Not confirmed
share of stake is being verified. Why
Disclosed plan
Adeoye Olukotun
Director
$851K
12K shares
Not confirmed
share of stake is being verified. Why
80% under a disclosed plan 20% no plan disclosed
Victoria Vakiener
Director
$679K
10K shares
Not confirmed
share of stake is being verified. Why
Disclosed plan
William Waddill
Director
$566K
8.4K shares
Not confirmed
share of stake is being verified. Why
Disclosed plan
Hongbo Lu
Director
$228K
3K shares
Not confirmed
share of stake is being verified. Why
Disclosed plan
The full ownership picture0 of 12 officers and directors confirmed

Vested shares across all share classes, held directly and through trusts, LLCs and family members, as reported on SEC Forms 3, 4 and 5. Unvested awards and options are never counted as owned shares.

InsiderHeld Oct 16, 2025SoldHeld Oct 16, 2026Still held
Christopher Anzalone
!
Holdings and share of stake are being verified. Share-of-stake figures and holdings for this company are held back while they are verified. Sales and other transactions for Christopher Anzalone are complete.
Chief Executive Officer, Director
n/a−360Kn/an/a
Vesting, gifts, unvested awards and holding lines for Christopher Anzalone

Holdings and share of stake are being verified. Sales, proceeds, plan and tax status and dates for Christopher Anzalone are complete; balances and unit counts will be added when the check is finished.

0gifted (net of own trusts)

Stock options (not counted as shares):

Options heldStrike priceExpiresIntrinsic value (estimate)
351,726$14.54Feb 6, 2024$25.5M
51,726$7.75Mar 6, 2025$4.1M

Estimate: options held × ($86.96 − strike price), using the most recent insider trade price on Form 4 (Aug 18, 2026), not a market close.

Patrick O'Brien
!
Holdings and share of stake are being verified. Share-of-stake figures and holdings for this company are held back while they are verified. Sales and other transactions for Patrick O'Brien are complete.
COO
n/a−49Kn/an/a
Vesting, gifts, unvested awards and holding lines for Patrick O'Brien

Holdings and share of stake are being verified. Sales, proceeds, plan and tax status and dates for Patrick O'Brien are complete; balances and unit counts will be added when the check is finished.

−5.3Kgifted (net of own trusts)
James Hamilton
!
Holdings and share of stake are being verified. Share-of-stake figures and holdings for this company are held back while they are verified. Sales and other transactions for James Hamilton are complete.
Chief Medical Officer
n/a−60Kn/an/a
Vesting, gifts, unvested awards and holding lines for James Hamilton

Holdings and share of stake are being verified. Sales, proceeds, plan and tax status and dates for James Hamilton are complete; balances and unit counts will be added when the check is finished.

0gifted (net of own trusts)
Michael Perry
!
Holdings and share of stake are being verified. Share-of-stake figures and holdings for this company are held back while they are verified. Sales and other transactions for Michael Perry are complete.
Director
n/a−28Kn/an/a
Vesting, gifts, unvested awards and holding lines for Michael Perry

Holdings and share of stake are being verified. Sales, proceeds, plan and tax status and dates for Michael Perry are complete; balances and unit counts will be added when the check is finished.

0gifted (net of own trusts)
Mauro Ferrari
!
Holdings and share of stake are being verified. Share-of-stake figures and holdings for this company are held back while they are verified. Sales and other transactions for Mauro Ferrari are complete.
Director
n/a−16Kn/an/a
Vesting, gifts, unvested awards and holding lines for Mauro Ferrari

Holdings and share of stake are being verified. Sales, proceeds, plan and tax status and dates for Mauro Ferrari are complete; balances and unit counts will be added when the check is finished.

0gifted (net of own trusts)
William Waddill
!
Holdings and share of stake are being verified. Share-of-stake figures and holdings for this company are held back while they are verified. Sales and other transactions for William Waddill are complete.
Director
n/a−8.4Kn/an/a
Vesting, gifts, unvested awards and holding lines for William Waddill

Holdings and share of stake are being verified. Sales, proceeds, plan and tax status and dates for William Waddill are complete; balances and unit counts will be added when the check is finished.

0gifted (net of own trusts)
Hongbo Lu
!
Holdings and share of stake are being verified. Share-of-stake figures and holdings for this company are held back while they are verified. Sales and other transactions for Hongbo Lu are complete.
Director
n/a−3Kn/an/a
Vesting, gifts, unvested awards and holding lines for Hongbo Lu

Holdings and share of stake are being verified. Sales, proceeds, plan and tax status and dates for Hongbo Lu are complete; balances and unit counts will be added when the check is finished.

0gifted (net of own trusts)
Douglas Ingram
!
Holdings and share of stake are being verified. Share-of-stake figures and holdings for this company are held back while they are verified. Sales and other transactions for Douglas Ingram are complete.
Director
n/a0n/an/a
Vesting, gifts, unvested awards and holding lines for Douglas Ingram

Holdings and share of stake are being verified. Sales, proceeds, plan and tax status and dates for Douglas Ingram are complete; balances and unit counts will be added when the check is finished.

0gifted (net of own trusts)
Victoria Vakiener
!
Holdings and share of stake are being verified. Share-of-stake figures and holdings for this company are held back while they are verified. Sales and other transactions for Victoria Vakiener are complete.
Director
n/a−10Kn/an/a
Vesting, gifts, unvested awards and holding lines for Victoria Vakiener

Holdings and share of stake are being verified. Sales, proceeds, plan and tax status and dates for Victoria Vakiener are complete; balances and unit counts will be added when the check is finished.

0gifted (net of own trusts)
Adeoye Olukotun
!
Holdings and share of stake are being verified. Share-of-stake figures and holdings for this company are held back while they are verified. Sales and other transactions for Adeoye Olukotun are complete.
Director
n/a−12Kn/an/a
Vesting, gifts, unvested awards and holding lines for Adeoye Olukotun

Holdings and share of stake are being verified. Sales, proceeds, plan and tax status and dates for Adeoye Olukotun are complete; balances and unit counts will be added when the check is finished.

0gifted (net of own trusts)
Daniel Apel
!
Holdings and share of stake are being verified. Share-of-stake figures and holdings for this company are held back while they are verified. Sales and other transactions for Daniel Apel are complete.
Chief Financial Officer
n/a−13Kn/an/a
Vesting, gifts, unvested awards and holding lines for Daniel Apel

Holdings and share of stake are being verified. Sales, proceeds, plan and tax status and dates for Daniel Apel are complete; balances and unit counts will be added when the check is finished.

0gifted (net of own trusts)
Matthew Cohen
!
Holdings and share of stake are being verified. Share-of-stake figures and holdings for this company are held back while they are verified. Sales and other transactions for Matthew Cohen are complete.
Director
n/a0n/an/a
Vesting, gifts, unvested awards and holding lines for Matthew Cohen

Holdings and share of stake are being verified. Sales, proceeds, plan and tax status and dates for Matthew Cohen are complete; balances and unit counts will be added when the check is finished.

0gifted (net of own trusts)

Holdings and share of stake for Arrowhead Pharmaceuticals, Inc. are being verified, so no balances, unit counts or percentages are shown. Sales, proceeds, plan and tax status, titles and dates come straight from individual filings.

What explains the selling$37.3M of sales by plan status, purpose, seller and month

Officer and director open-market sales: $37.3M across 560,501 shares. Plan status and stated purpose are separate questions, and a sale can have both.

By plan status

The lighter segment is sales with no plan disclosed in the filing ($20.5M), including tax-related sales outside a plan.

No plan disclosed · $2.7M

Sales with no 10b5-1 plan and no tax reference in the filing. $2.0M of it is Michael Perry. No plan disclosed is a statement about the filing, not about why the sale happened. Largest such sale: Michael Perry, Aug 18, 2026

Taxes

$24.6M of sales (66.0%) cite tax obligations in their footnotes, $6.8M of them also under a plan. Example: Daniel Apel, Apr 22, 2026

SellerShares soldProceedsUnder a disclosed planShare of totalSales dates
Christopher Anzalone
Chief Executive Officer, Director
360K$24.0M26%64%Dec 15, 2025 to Jan 2, 2026
James Hamilton
Chief Medical Officer
60K$3.9M100%11%Jan 5, 2026 to Apr 23, 2026
Patrick O'Brien
COO
49K$3.1M100%8%Jan 5, 2026 to Jan 5, 2026
Michael Perry
Director
28K$2.0M0%5%Dec 5, 2025 to Aug 18, 2026
Mauro Ferrari
Director
16K$1.0M52%3%Nov 28, 2025 to Dec 26, 2025
Daniel Apel
Chief Financial Officer
13K$934K100%3%Apr 22, 2026 to Apr 22, 2026
Adeoye Olukotun
Director
12K$851K80%2%Dec 19, 2025 to Aug 18, 2026
Victoria Vakiener
Director
10K$679K100%2%Dec 19, 2025 to Dec 19, 2025
William Waddill
Director
8.4K$566K100%2%Dec 19, 2025 to Dec 19, 2025
Hongbo Lu
Director
3K$228K100%0.6%May 12, 2026 to May 12, 2026

Sales by month

MonthSale proceedsDisclosed planTo cover taxesNo plan disclosed
Oct 2025$0$0$0$0
Nov 2025$493K$0$0$493K
Dec 2025$26.6M$7.8M$17.8M$992K
Jan 2026$6.5M$6.5M$0$0
Feb 2026$0$0$0$0
Mar 2026$642K$642K$0$0
Apr 2026$1.7M$1.7M$0$0
May 2026$228K$228K$0$0
Jun 2026$0$0$0$0
Jul 2026$0$0$0$0
Aug 2026$1.2M$0$0$1.2M
Sep 2026$0$0$0$0
Oct 2026$0$0$0$0
Is this normal? Selling year by year5 earlier years to compare with

In line with the past 5 years. 10 insiders sold; the average is 10 a year.

12 months endingShares soldInsiders who soldProceeds
Oct 16, 2026
Latest 12 months
561K10$37.3M
Oct 16, 2025
1 year earlier
744K8$13.2M
Oct 16, 2024
2 years earlier
299K10$9.7M
Oct 17, 2023
3 years earlier
320K10$11.5M
Oct 17, 2022
4 years earlier
410K10$24.8M
Oct 17, 2021
5 years earlier
553K12$39.6M

Open-market sales (Form 4 code S) by people who were officers or directors, in split-adjusted shares. Earlier years include people who have since left. A sale that an outside holder also reports (a family trust, a fund) is counted with outside holders in every year. Shares, not dollars, are compared, so a change in the stock price doesn't look like a change in selling. Years the filings don't fully cover are shown but left out of the average.

Known gaps and uncertainty12 officers and directors not confirmed

Holdings and share of stake are being verified. Balances, unit counts and every share-of-stake figure for Arrowhead Pharmaceuticals, Inc. are held back until that check is finished. Sales, proceeds, plan and tax status, titles and dates come straight from individual filings and are complete.

External context: we only cite outside events when a documented connection exists. None is shown for this period.

Sources and methodology497 filings on record, 31 filed in the 12-month period, and how we read them

All 497 Forms 3, 4 and 5 on record for Arrowhead Pharmaceuticals, Inc. (SEC CIK 879407), filed from Feb 3, 2004 to Aug 20, 2026; 31 of them were filed in the 12 months this page covers, retrieved from SEC EDGAR on Oct 16, 2026. Prices are the ones reported in each filing, often weighted averages.

Probable 1-for-10 stock split on or before Oct 9, 2013 (first filing that shows post-split balances). Splits aren't reported as transactions; 4 holding lines changed by exactly this ratio, so earlier share counts are restated.

Holdings. Each holding line (a share class plus an owner, such as a trust or LLC) carries its last reported balance forward. Entities first reported during the period start at zero, so transfers between an insider's own trusts don't count as selling. Lines not reported for three years or more are listed separately and left out of totals.

Sales. A sale counts as under a 10b5-1 plan if its footnote cites one or the filing's Rule 10b5-1 box is checked, and as tax-related if its footnote cites tax obligations or sell-to-cover. Shares withheld by the company for taxes are listed separately. Sales with neither attribute are labeled "no plan disclosed".

Full methodology

Former or inactive filers (26)No filing in 18 months; last reported balances, not in any total
NameLast filedLast reported balance
Kenneth MyszkowskiJan 7, 2025455,433 shares, last reported balance as of Jan 7, 2025
Douglas GivenDec 18, 2024149,667 shares, last reported balance as of Dec 17, 2024
Tracie OliverJul 3, 2024127,107 shares, last reported balance as of Jul 2, 2024
Martin SanJan 8, 2024198,497 shares, last reported balance as of Jan 5, 2024
Marianne De BackerJan 11, 20234,593 shares, last reported balance as of Jan 10, 2023
James HassardJun 24, 2021105,750 shares, last reported balance as of Jun 22, 2021
Curt BradshawNov 23, 2020No balance on record
Bruce GivenApr 29, 2020850,730 shares, last reported balance as of Apr 28, 2020
Zhen LiJan 16, 2019201,700 shares, last reported balance as of Jan 14, 2019
Peter LeoneOct 23, 2018130,000 shares, last reported balance as of Oct 19, 2018
Edward FrykmanJan 3, 2018153,852 shares, last reported balance as of Jan 1, 2018
David LewisJan 4, 2016No balance on record
Charles McKenneyMar 6, 201543,240 shares, last reported balance as of Mar 4, 2015
Bruce StewartMar 8, 201051,150 shares, last reported balance as of May 20, 2009
Leroy RahnMar 8, 2010No balance on record
Paul McDonnelAug 24, 2009No balance on record
Larry StambaughNov 13, 2007No balance on record
Arthur SwiftJun 28, 2007No balance on record
Joseph Kingsley IIIApr 9, 20071,200 shares, last reported balance as of Jan 10, 2007
David KnottMar 22, 2007679,764 shares, last reported balance as of Mar 21, 2007
Edward JacobsJan 22, 2007No balance on record
John PetrovichJan 22, 20071,547 shares, last reported balance as of Jan 1, 2007
Leon EkchianNov 21, 2005No balance on record
Marshall ChingJun 27, 2005581,228 shares, last reported balance as of Jun 23, 2005
James Phillips Jr.Apr 16, 200415,000 shares, last reported balance as of Jan 30, 2004
Charles CollierFeb 11, 2004No balance on record

Spotted something wrong on this page? Report an error. We check every report against the SEC filing and list what we fix in the corrections log.