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ALNYAlnylam Pharmaceuticals, Inc. · Insider ownership research

Alnylam Pharmaceuticals, Inc. insiders sold $44.0M in the past 12 months. How much of their stake is that?

63% was sold under disclosed trading plans, 37% to cover taxes. The largest seller, Yvonne Greenstreet (Chief Executive Officer, Director), sold $20.4M. 63% of these sales were shares from exercising options.Share-of-stake figures for this company are being verified and will be added when that check is finished. Why

Updated Oct 16, 2026 from SEC filings · covers Oct 17, 2025 to Oct 16, 2026
$20.4M
largest seller, Yvonne Greenstreet, past 12 months
63%
of sales were under disclosed trading plans, past 12 months
8 of 19
officers and directors sold shares, past 12 months
Is this normal? Less than usual: about half of the 5-year average. 8 insiders sold; the average is 8 a year. Year by year
Latest filing: Filed Oct 6 for a sale on Oct 2. Bryan Supran sold 1.8K shares ($399K) to cover taxes on vesting stock. Filing
SEC ownership filings: 48 filed in the 12 months to Oct 16, 2026; 910 on record since May 27, 2004 · See the evidence

What stands out

Routine activity: 63% of sales were under disclosed plans, and no insider sold more than 1% of vested holdings.

A share of stake is shown for 0 of the 8 officers and directors who sold. 19 are left out

i
Left out: Yvonne Greenstreet, Jeffrey Poulton, David Pyott, Tolga Tanguler, Kevin Fitzgerald, Pushkal Garg, Michael Bonney, Bryan Supran, Amy Schulman, Dennis Ausiello, Charles Sigal, Margaret Hamburg, Colleen Reitan, Olivier Brandicourt, Carolyn Bertozzi, Peter Kellogg, Stuart Arbuckle, Melissa McLaughlin and Benjamin Cravatt (share of stake is being verified).
Disclosed company stock is not an insider's whole wealth.

Who sold, and how much of their stake

Officers and directors, past 12 months. Their share of stake is being verified and is not shown yet; amounts and trading plans are below.

Yvonne Greenstreet
Chief Executive Officer, Director
Not confirmed
Share of stake not shown: share of stake is being verified. Why
$20.4M57% planned, 43% to cover taxes
Kevin Fitzgerald
CSO & EVP, Head of Research
Not confirmed
Share of stake not shown: share of stake is being verified. Why
$9.6MDisclosed plan
Pushkal Garg
EVP Chief R&D
Not confirmed
Share of stake not shown: share of stake is being verified. Why
$5.4M77% planned, 23% to cover taxes
Jeffrey Poulton
EVP, Chief Financial Officer
Not confirmed
Share of stake not shown: share of stake is being verified. Why
$3.2MTo cover taxes
Tolga Tanguler
EVP, Chief Commercial Officer
Not confirmed
Share of stake not shown: share of stake is being verified. Why
$2.4MTo cover taxes
All 8 sellers

Selling by month

Officers and directors, Oct 2025 to Oct 2026. Each sale is counted once: under a disclosed plan, else to cover taxes, else no plan disclosed.

Disclosed planTo cover taxesOne dollar scale for every month; the tallest bar is labeled
OctNov 2025: $17.1M under a disclosed plan$17.1MNovDecJan 2026: $1.4M under a disclosed planJan 2026: $5.6M to cover taxesJanFeb 2026: $2.8M under a disclosed planFeb 2026: $4.2M to cover taxesFebMar 2026: $4.1M under a disclosed planMar 2026: $6.0M to cover taxesMarApr 2026: $1.3M under a disclosed planAprMayJun 2026: $1.1M under a disclosed planJunJulAugSepOct 2026: $399K to cover taxesOct

Recent activity

Past 30 days, Sep 17, 2026 to Oct 16, 2026
Oct 2, 2026Bryan Supran sold 1.8K shares ($399K) to cover taxes on vesting stock.
WhoSharesPrice% of total stakeTotal stake afterTrade dateFiled
Bryan Supran
EVP, CLO and Secretary
1,758$226.88n/an/aOct 2, 2026Oct 6, 2026

"% of total stake" is the shares in an event against all the vested shares the person held that day, across every share class and holding entity, after that day's vesting. "n/a" means the person's holdings are not confirmed, or the row is a purchase. "Holdings record incomplete" means more shares were sold than the filings show the person held that day, so a percentage would be wrong.

Common questions

Is the Alnylam Pharmaceuticals, Inc. CEO selling stock?

Yes. Yvonne Greenstreet sold 52K shares ($20.4M) in the past 12 months, 57% of it under a trading plan disclosed in the filings.

Why are Alnylam Pharmaceuticals, Inc. insiders selling?

Filings rarely give a reason, and we don't guess at one. What they show is how the sales were made: 63% of sales by value ran under 10b5-1 trading plans disclosed in the filings and 37% were to cover taxes. A trading plan schedules sales in advance.

Are any Alnylam Pharmaceuticals, Inc. insiders buying?

No. Officers and directors reported no purchases in the past 12 months.

The evidence

Who sold8 officers and directors: amount, % of holdings, trading plan
Who soldAmount% of holdingsTrading plan
Yvonne Greenstreet
Chief Executive Officer, Director
$20.4M
52K shares
Not confirmed
share of stake is being verified. Why
57% under a disclosed plan, 43% to cover taxes
Kevin Fitzgerald
CSO & EVP, Head of Research
$9.6M
24K shares
Not confirmed
share of stake is being verified. Why
Disclosed plan
Pushkal Garg
EVP Chief R&D
$5.4M
17K shares
Not confirmed
share of stake is being verified. Why
77% under a disclosed plan, 23% to cover taxes
Jeffrey Poulton
EVP, Chief Financial Officer
$3.2M
9.7K shares
Not confirmed
share of stake is being verified. Why
To cover taxes
Tolga Tanguler
EVP, Chief Commercial Officer
$2.4M
7.4K shares
Not confirmed
share of stake is being verified. Why
To cover taxes
Melissa McLaughlin
Chief Human Resources Officer
$1.3M
3.9K shares
Not confirmed
share of stake is being verified. Why
Disclosed plan
David Pyott
Director
$1.1M
3.8K shares
Not confirmed
share of stake is being verified. Why
Disclosed plan
Bryan Supran
EVP, CLO and Secretary
$399K
1.8K shares
Not confirmed
share of stake is being verified. Why
To cover taxes
The full ownership picture0 of 19 officers and directors confirmed

Vested shares across all share classes, held directly and through trusts, LLCs and family members, as reported on SEC Forms 3, 4 and 5. Unvested awards and options are never counted as owned shares.

InsiderHeld Oct 16, 2025SoldHeld Oct 16, 2026Still held
Yvonne Greenstreet
!
Holdings and share of stake are being verified. Share-of-stake figures and holdings for this company are held back while they are verified. Sales and other transactions for Yvonne Greenstreet are complete.
Chief Executive Officer, Director
n/a−52Kn/an/a
Vesting, gifts, unvested awards and holding lines for Yvonne Greenstreet

Holdings and share of stake are being verified. Sales, proceeds, plan and tax status and dates for Yvonne Greenstreet are complete; balances and unit counts will be added when the check is finished.

0gifted (net of own trusts)
−1.1Kwithheld by the company for taxes

Stock options (not counted as shares):

Options heldStrike priceExpiresIntrinsic value (estimate)
28,141$151.59Feb 23, 2031$2.1M
46,394$152.61Mar 1, 2034$3.4M
36,293$243.53Mar 3, 2035$0
30,425$325.07Mar 2, 2036$0

Estimate: options held × ($226.88 − strike price), using the most recent insider trade price on Form 4 (Oct 2, 2026), not a market close.

Jeffrey Poulton
!
Holdings and share of stake are being verified. Share-of-stake figures and holdings for this company are held back while they are verified. Sales and other transactions for Jeffrey Poulton are complete.
EVP, Chief Financial Officer
n/a−9.7Kn/an/a
Vesting, gifts, unvested awards and holding lines for Jeffrey Poulton

Holdings and share of stake are being verified. Sales, proceeds, plan and tax status and dates for Jeffrey Poulton are complete; balances and unit counts will be added when the check is finished.

0gifted (net of own trusts)
  • Some sales match sales reported by Pushkal Garg exactly (date, shares and price). Possibly the same shares reported by both; the filings don't confirm it.

Stock options (not counted as shares):

Options heldStrike priceExpiresIntrinsic value (estimate)
15,118$152.61Mar 1, 2034$1.1M
9,800$243.53Mar 3, 2035$0
10,480$325.07Mar 2, 2036$0

Estimate: options held × ($226.88 − strike price), using the most recent insider trade price on Form 4 (Oct 2, 2026), not a market close.

David Pyott
!
Holdings and share of stake are being verified. Share-of-stake figures and holdings for this company are held back while they are verified. Sales and other transactions for David Pyott are complete.
Director
n/a−3.8Kn/an/a
Vesting, gifts, unvested awards and holding lines for David Pyott

Holdings and share of stake are being verified. Sales, proceeds, plan and tax status and dates for David Pyott are complete; balances and unit counts will be added when the check is finished.

0gifted (net of own trusts)

Stock options (not counted as shares):

Options heldStrike priceExpiresIntrinsic value (estimate)
3,780$71.99Jun 1, 2027$585K
5,228$151.22May 16, 2034$396K
1,558$258.35May 8, 2035$0
1,441$298.48May 20, 2036$0

Estimate: options held × ($226.88 − strike price), using the most recent insider trade price on Form 4 (Oct 2, 2026), not a market close.

Tolga Tanguler
!
Holdings and share of stake are being verified. Share-of-stake figures and holdings for this company are held back while they are verified. Sales and other transactions for Tolga Tanguler are complete.
EVP, Chief Commercial Officer
n/a−7.4Kn/an/a
Vesting, gifts, unvested awards and holding lines for Tolga Tanguler

Holdings and share of stake are being verified. Sales, proceeds, plan and tax status and dates for Tolga Tanguler are complete; balances and unit counts will be added when the check is finished.

0gifted (net of own trusts)
  • Some sales match sales reported by Kevin Fitzgerald exactly (date, shares and price). Possibly the same shares reported by both; the filings don't confirm it.
  • Some sales match sales reported by Pushkal Garg exactly (date, shares and price). Possibly the same shares reported by both; the filings don't confirm it.

Stock options (not counted as shares):

Options heldStrike priceExpiresIntrinsic value (estimate)
9,279$152.61Mar 1, 2034$689K
7,819$243.53Mar 3, 2035$0
10,480$325.07Mar 2, 2036$0

Estimate: options held × ($226.88 − strike price), using the most recent insider trade price on Form 4 (Oct 2, 2026), not a market close.

Kevin Fitzgerald
!
Holdings and share of stake are being verified. Share-of-stake figures and holdings for this company are held back while they are verified. Sales and other transactions for Kevin Fitzgerald are complete.
CSO & EVP, Head of Research
n/a−24Kn/an/a
Vesting, gifts, unvested awards and holding lines for Kevin Fitzgerald

Holdings and share of stake are being verified. Sales, proceeds, plan and tax status and dates for Kevin Fitzgerald are complete; balances and unit counts will be added when the check is finished.

0gifted (net of own trusts)
  • Some sales match sales reported by Tolga Tanguler exactly (date, shares and price). Possibly the same shares reported by both; the filings don't confirm it.

Stock options (not counted as shares):

Options heldStrike priceExpiresIntrinsic value (estimate)
9,000$119.13Mar 1, 2028$970K
2,192$85.00Feb 28, 2029$311K
14,580$118.05Feb 26, 2030$1.6M
839$119.13Mar 1, 2028$90K
20,382$147.47Feb 23, 2032$1.6M
15,692$151.59Feb 24, 2031$1.2M
9,279$152.61Mar 1, 2034$689K
10,352$190.01Feb 27, 2033$382K
7,819$243.53Mar 3, 2035$0
8,105$325.07Mar 2, 2036$0

Estimate: options held × ($226.88 − strike price), using the most recent insider trade price on Form 4 (Oct 2, 2026), not a market close.

Pushkal Garg
!
Holdings and share of stake are being verified. Share-of-stake figures and holdings for this company are held back while they are verified. Sales and other transactions for Pushkal Garg are complete.
EVP Chief R&D
n/a−17Kn/an/a
Vesting, gifts, unvested awards and holding lines for Pushkal Garg

Holdings and share of stake are being verified. Sales, proceeds, plan and tax status and dates for Pushkal Garg are complete; balances and unit counts will be added when the check is finished.

0gifted (net of own trusts)
  • Some sales match sales reported by Jeffrey Poulton exactly (date, shares and price). Possibly the same shares reported by both; the filings don't confirm it.
  • Some sales match sales reported by Tolga Tanguler exactly (date, shares and price). Possibly the same shares reported by both; the filings don't confirm it.

Stock options (not counted as shares):

Options heldStrike priceExpiresIntrinsic value (estimate)
9,279$152.61Mar 1, 2034$689K
7,819$243.53Mar 3, 2035$0
10,480$325.07Mar 2, 2036$0

Estimate: options held × ($226.88 − strike price), using the most recent insider trade price on Form 4 (Oct 2, 2026), not a market close.

Michael Bonney
!
Holdings and share of stake are being verified. Share-of-stake figures and holdings for this company are held back while they are verified. Sales and other transactions for Michael Bonney are complete.
Director
n/a0n/an/a
Vesting, gifts, unvested awards and holding lines for Michael Bonney

Holdings and share of stake are being verified. Sales, proceeds, plan and tax status and dates for Michael Bonney are complete; balances and unit counts will be added when the check is finished.

0gifted (net of own trusts)

Stock options (not counted as shares):

Options heldStrike priceExpiresIntrinsic value (estimate)
5,228$151.22May 16, 2034$396K
1,558$258.35May 8, 2035$0

Estimate: options held × ($226.88 − strike price), using the most recent insider trade price on Form 4 (Oct 2, 2026), not a market close.

Bryan Supran
!
Holdings and share of stake are being verified. Share-of-stake figures and holdings for this company are held back while they are verified. Sales and other transactions for Bryan Supran are complete.
EVP, CLO and Secretary
n/a−1.8Kn/an/a
Vesting, gifts, unvested awards and holding lines for Bryan Supran

Holdings and share of stake are being verified. Sales, proceeds, plan and tax status and dates for Bryan Supran are complete; balances and unit counts will be added when the check is finished.

0gifted (net of own trusts)

Stock options (not counted as shares):

Options heldStrike priceExpiresIntrinsic value (estimate)
3,381$325.07Mar 2, 2036$0

Estimate: options held × ($226.88 − strike price), using the most recent insider trade price on Form 4 (Oct 2, 2026), not a market close.

Amy Schulman
!
Holdings and share of stake are being verified. Share-of-stake figures and holdings for this company are held back while they are verified. Sales and other transactions for Amy Schulman are complete.
Director
n/a0n/an/a
Vesting, gifts, unvested awards and holding lines for Amy Schulman

Holdings and share of stake are being verified. Sales, proceeds, plan and tax status and dates for Amy Schulman are complete; balances and unit counts will be added when the check is finished.

0gifted (net of own trusts)

Stock options (not counted as shares):

Options heldStrike priceExpiresIntrinsic value (estimate)
5,228$151.22May 16, 2034$396K
1,558$258.35May 8, 2035$0
1,802$298.48May 20, 2036$0

Estimate: options held × ($226.88 − strike price), using the most recent insider trade price on Form 4 (Oct 2, 2026), not a market close.

Dennis Ausiello
!
Holdings and share of stake are being verified. Share-of-stake figures and holdings for this company are held back while they are verified. Sales and other transactions for Dennis Ausiello are complete.
Director
n/a0n/an/a
Vesting, gifts, unvested awards and holding lines for Dennis Ausiello

Holdings and share of stake are being verified. Sales, proceeds, plan and tax status and dates for Dennis Ausiello are complete; balances and unit counts will be added when the check is finished.

0gifted (net of own trusts)

Stock options (not counted as shares):

Options heldStrike priceExpiresIntrinsic value (estimate)
1,558$258.35May 8, 2035$0
1,441$298.48May 20, 2036$0

Estimate: options held × ($226.88 − strike price), using the most recent insider trade price on Form 4 (Oct 2, 2026), not a market close.

Charles Sigal
!
Holdings and share of stake are being verified. Share-of-stake figures and holdings for this company are held back while they are verified. Sales and other transactions for Charles Sigal are complete.
Director
n/a0n/an/a
Vesting, gifts, unvested awards and holding lines for Charles Sigal

Holdings and share of stake are being verified. Sales, proceeds, plan and tax status and dates for Charles Sigal are complete; balances and unit counts will be added when the check is finished.

0gifted (net of own trusts)

Stock options (not counted as shares):

Options heldStrike priceExpiresIntrinsic value (estimate)
5,228$151.22May 16, 2034$396K
1,558$258.35May 8, 2035$0
1,441$298.48May 20, 2036$0

Estimate: options held × ($226.88 − strike price), using the most recent insider trade price on Form 4 (Oct 2, 2026), not a market close.

Margaret Hamburg
!
Holdings and share of stake are being verified. Share-of-stake figures and holdings for this company are held back while they are verified. Sales and other transactions for Margaret Hamburg are complete.
Director
n/a0n/an/a
Vesting, gifts, unvested awards and holding lines for Margaret Hamburg

Holdings and share of stake are being verified. Sales, proceeds, plan and tax status and dates for Margaret Hamburg are complete; balances and unit counts will be added when the check is finished.

0gifted (net of own trusts)

Stock options (not counted as shares):

Options heldStrike priceExpiresIntrinsic value (estimate)
5,228$151.22May 16, 2034$396K
1,558$258.35May 8, 2035$0
1,441$298.48May 20, 2036$0

Estimate: options held × ($226.88 − strike price), using the most recent insider trade price on Form 4 (Oct 2, 2026), not a market close.

Colleen Reitan
!
Holdings and share of stake are being verified. Share-of-stake figures and holdings for this company are held back while they are verified. Sales and other transactions for Colleen Reitan are complete.
Director
n/a0n/an/a
Vesting, gifts, unvested awards and holding lines for Colleen Reitan

Holdings and share of stake are being verified. Sales, proceeds, plan and tax status and dates for Colleen Reitan are complete; balances and unit counts will be added when the check is finished.

0gifted (net of own trusts)

Stock options (not counted as shares):

Options heldStrike priceExpiresIntrinsic value (estimate)
5,228$151.22May 16, 2034$396K
1,558$258.35May 8, 2035$0
1,441$298.48May 20, 2036$0

Estimate: options held × ($226.88 − strike price), using the most recent insider trade price on Form 4 (Oct 2, 2026), not a market close.

Olivier Brandicourt
!
Holdings and share of stake are being verified. Share-of-stake figures and holdings for this company are held back while they are verified. Sales and other transactions for Olivier Brandicourt are complete.
Director
n/a0n/an/a
Vesting, gifts, unvested awards and holding lines for Olivier Brandicourt

Holdings and share of stake are being verified. Sales, proceeds, plan and tax status and dates for Olivier Brandicourt are complete; balances and unit counts will be added when the check is finished.

0gifted (net of own trusts)

Stock options (not counted as shares):

Options heldStrike priceExpiresIntrinsic value (estimate)
5,228$151.22May 16, 2034$396K
1,558$258.35May 8, 2035$0
1,441$298.48May 20, 2036$0

Estimate: options held × ($226.88 − strike price), using the most recent insider trade price on Form 4 (Oct 2, 2026), not a market close.

Carolyn Bertozzi
!
Holdings and share of stake are being verified. Share-of-stake figures and holdings for this company are held back while they are verified. Sales and other transactions for Carolyn Bertozzi are complete.
Director
n/a0n/an/a
Vesting, gifts, unvested awards and holding lines for Carolyn Bertozzi

Holdings and share of stake are being verified. Sales, proceeds, plan and tax status and dates for Carolyn Bertozzi are complete; balances and unit counts will be added when the check is finished.

0gifted (net of own trusts)

Stock options (not counted as shares):

Options heldStrike priceExpiresIntrinsic value (estimate)
5,228$151.22May 16, 2034$396K
1,558$258.35May 8, 2035$0

Estimate: options held × ($226.88 − strike price), using the most recent insider trade price on Form 4 (Oct 2, 2026), not a market close.

Peter Kellogg
!
Holdings and share of stake are being verified. Share-of-stake figures and holdings for this company are held back while they are verified. Sales and other transactions for Peter Kellogg are complete.
Director
n/a0n/an/a
Vesting, gifts, unvested awards and holding lines for Peter Kellogg

Holdings and share of stake are being verified. Sales, proceeds, plan and tax status and dates for Peter Kellogg are complete; balances and unit counts will be added when the check is finished.

0gifted (net of own trusts)

Stock options (not counted as shares):

Options heldStrike priceExpiresIntrinsic value (estimate)
5,228$151.22May 16, 2034$396K
1,558$258.35May 8, 2035$0
1,441$298.48May 20, 2036$0

Estimate: options held × ($226.88 − strike price), using the most recent insider trade price on Form 4 (Oct 2, 2026), not a market close.

Stuart Arbuckle
!
Holdings and share of stake are being verified. Share-of-stake figures and holdings for this company are held back while they are verified. Sales and other transactions for Stuart Arbuckle are complete.
Director
n/a0n/an/a
Vesting, gifts, unvested awards and holding lines for Stuart Arbuckle

Holdings and share of stake are being verified. Sales, proceeds, plan and tax status and dates for Stuart Arbuckle are complete; balances and unit counts will be added when the check is finished.

0gifted (net of own trusts)

Stock options (not counted as shares):

Options heldStrike priceExpiresIntrinsic value (estimate)
3,279$397.83Jan 5, 2036$0
1,441$298.48May 20, 2036$0

Estimate: options held × ($226.88 − strike price), using the most recent insider trade price on Form 4 (Oct 2, 2026), not a market close.

Melissa McLaughlin
!
Holdings and share of stake are being verified. Share-of-stake figures and holdings for this company are held back while they are verified. Sales and other transactions for Melissa McLaughlin are complete.
Chief Human Resources Officer
n/a−3.9Kn/an/a
Vesting, gifts, unvested awards and holding lines for Melissa McLaughlin

Holdings and share of stake are being verified. Sales, proceeds, plan and tax status and dates for Melissa McLaughlin are complete; balances and unit counts will be added when the check is finished.

0gifted (net of own trusts)

Stock options (not counted as shares):

Options heldStrike priceExpiresIntrinsic value (estimate)
3,567$325.07Mar 2, 2036$0

Estimate: options held × ($226.88 − strike price), using the most recent insider trade price on Form 4 (Oct 2, 2026), not a market close.

Benjamin Cravatt
!
Holdings and share of stake are being verified. Share-of-stake figures and holdings for this company are held back while they are verified. Sales and other transactions for Benjamin Cravatt are complete.
Director
n/a0n/an/a
Vesting, gifts, unvested awards and holding lines for Benjamin Cravatt

Holdings and share of stake are being verified. Sales, proceeds, plan and tax status and dates for Benjamin Cravatt are complete; balances and unit counts will be added when the check is finished.

0gifted (net of own trusts)

Stock options (not counted as shares):

Options heldStrike priceExpiresIntrinsic value (estimate)
4,393$295.63Jun 1, 2036$0

Estimate: options held × ($226.88 − strike price), using the most recent insider trade price on Form 4 (Oct 2, 2026), not a market close.

Holdings and share of stake for Alnylam Pharmaceuticals, Inc. are being verified, so no balances, unit counts or percentages are shown. Sales, proceeds, plan and tax status, titles and dates come straight from individual filings.

What explains the selling$44.0M of sales by plan status, purpose, seller and month

Officer and director open-market sales: $44.0M across 119,540 shares. Plan status and stated purpose are separate questions, and a sale can have both.

By plan status

The lighter segment is sales with no plan disclosed in the filing ($16.1M), including tax-related sales outside a plan.

Taxes

$19.8M of sales (45.1%) cite tax obligations in their footnotes, $3.7M of them also under a plan. Separately, 1,121 shares ($499K) were withheld by the company for taxes, which isn't a market sale. Example: Bryan Supran, Oct 2, 2026

SellerShares soldProceedsUnder a disclosed planShare of totalSales dates
Yvonne Greenstreet
Chief Executive Officer, Director
52K$20.4M57%46%Nov 12, 2025 to Mar 4, 2026
Kevin Fitzgerald
CSO & EVP, Head of Research
24K$9.6M100%22%Nov 17, 2025 to Mar 5, 2026
Pushkal Garg
EVP Chief R&D
17K$5.4M77%12%Jan 12, 2026 to Mar 5, 2026
Jeffrey Poulton
EVP, Chief Financial Officer
9.7K$3.2M0%7%Jan 12, 2026 to Mar 4, 2026
Tolga Tanguler
EVP, Chief Commercial Officer
7.4K$2.4M0%6%Jan 12, 2026 to Mar 4, 2026
Melissa McLaughlin
Chief Human Resources Officer
3.9K$1.3M100%3%Apr 2, 2026 to Apr 6, 2026
David Pyott
Director
3.8K$1.1M100%3%Jun 1, 2026 to Jun 1, 2026
Bryan Supran
EVP, CLO and Secretary
1.8K$399K0%0.9%Oct 2, 2026 to Oct 2, 2026

Sales by month

MonthSale proceedsDisclosed planTo cover taxesNo plan disclosed
Oct 2025$0$0$0$0
Nov 2025$17.1M$17.1M$0$0
Dec 2025$0$0$0$0
Jan 2026$7.0M$1.4M$5.6M$0
Feb 2026$7.0M$2.8M$4.2M$0
Mar 2026$10.1M$4.1M$6.0M$0
Apr 2026$1.3M$1.3M$0$0
May 2026$0$0$0$0
Jun 2026$1.1M$1.1M$0$0
Jul 2026$0$0$0$0
Aug 2026$0$0$0$0
Sep 2026$0$0$0$0
Oct 2026$399K$0$399K$0
Is this normal? Selling year by year5 earlier years to compare with

Less than usual: about half of the 5-year average. 8 insiders sold; the average is 8 a year.

12 months endingShares soldInsiders who soldProceeds
Oct 16, 2026
Latest 12 months
120K8$44.0M
Oct 16, 2025
1 year earlier
284K10$97.2M
Oct 16, 2024
2 years earlier
234K11$50.2M
Oct 17, 2023
3 years earlier
131K8$27.1M
Oct 17, 2022
4 years earlier
121K5$22.2M
Oct 17, 2021
5 years earlier
313K6$50.5M

Open-market sales (Form 4 code S) by people who were officers or directors, in split-adjusted shares. Earlier years include people who have since left. A sale that an outside holder also reports (a family trust, a fund) is counted with outside holders in every year. Shares, not dollars, are compared, so a change in the stock price doesn't look like a change in selling. Years the filings don't fully cover are shown but left out of the average.

Known gaps and uncertainty19 officers and directors not confirmed

Holdings and share of stake are being verified. Balances, unit counts and every share-of-stake figure for Alnylam Pharmaceuticals, Inc. are held back until that check is finished. Sales, proceeds, plan and tax status, titles and dates come straight from individual filings and are complete.

External context: we only cite outside events when a documented connection exists. None is shown for this period.

Sources and methodology910 filings on record, 48 filed in the 12-month period, and how we read them

All 910 Forms 3, 4 and 5 on record for Alnylam Pharmaceuticals, Inc. (SEC CIK 1178670), filed from May 27, 2004 to Oct 6, 2026; 48 of them were filed in the 12 months this page covers, retrieved from SEC EDGAR on Oct 16, 2026. Prices are the ones reported in each filing, often weighted averages. 22 filings were left out because Alnylam Pharmaceuticals, Inc. filed them as an owner of another company's stock.

Holdings. Each holding line (a share class plus an owner, such as a trust or LLC) carries its last reported balance forward. Entities first reported during the period start at zero, so transfers between an insider's own trusts don't count as selling. Lines not reported for three years or more are listed separately and left out of totals.

Sales. A sale counts as under a 10b5-1 plan if its footnote cites one or the filing's Rule 10b5-1 box is checked, and as tax-related if its footnote cites tax obligations or sell-to-cover. Shares withheld by the company for taxes are listed separately. Sales with neither attribute are labeled "no plan disclosed".

Full methodology

Former or inactive filers (45)No filing in 18 months; last reported balances, not in any total
NameLast filedLast reported balance
Robert HessleinMar 5, 20258,002 shares, last reported balance as of Mar 3, 2025
Phillip SharpJan 24, 2025645,633 shares, last reported balance as of Jan 23, 2025
Indrani FranchiniFeb 29, 20244,133 shares, last reported balance as of Feb 28, 2024
Akshay VaishnawAug 7, 202323,289 shares, last reported balance as of Aug 4, 2023
Marsha FanucciMay 19, 2023136 shares, last reported balance as of Feb 23, 2023
Steven PaulApr 5, 20221,000 shares, last reported balance as of Apr 1, 2022
John MaraganoreDec 23, 2021230,796 shares, last reported balance as of Dec 22, 2021
Laurie KeatingAug 9, 20215,566 shares, last reported balance as of Aug 5, 2021
Barry GreeneSep 11, 202076,987 shares, last reported balance as of Sep 9, 2020
Paul SchimmelJul 2, 2019306,996 shares, last reported balance as of Mar 13, 2018
Manmeet SoniMar 1, 201983 shares, last reported balance as of Jul 10, 2018
Michael MasonSep 28, 2018839 shares, last reported balance as of Aug 13, 2018
John ClarkeJun 22, 20182,100,759 shares, last reported balance as of May 31, 2018
John ClarkeJun 22, 20188,891 shares, last reported balance as of May 21, 2014
Kevin StarrJun 6, 2017No balance on record
SanofiJun 1, 201710,554,134 shares, last reported balance as of May 31, 2017
David-Alexandre GrosDec 22, 20161,000 shares, last reported balance as of Feb 22, 2016
Laurence ReidJan 5, 201519,869 shares, last reported balance as of Dec 31, 2014
Victor DzauJun 10, 2013No balance on record
NOVARTIS AGSep 24, 20124,051,002 shares, last reported balance as of Sep 20, 2012
Patricia AllenDec 10, 20101,165 shares, last reported balance as of Dec 8, 2010
Kenneth KoblanDec 10, 2010357 shares, last reported balance as of Dec 8, 2010
James VincentJun 18, 2010No balance on record
Vicki SatoJun 4, 2010No balance on record
Edward ScolnickJun 12, 2009No balance on record
John Schmidt Jr.Dec 11, 2008No balance on record
Peter BarrettJun 16, 2006328,877 shares, last reported balance as of Mar 7, 2006
Peter BarrettJun 16, 20062,979,807 shares, last reported balance as of Mar 7, 2006
ATLAS VENTURE FUND V LPFeb 27, 20063,354,250 shares, last reported balance as of Feb 24, 2006
Vincent MilesDec 9, 2005No balance on record
John BerrimanJun 10, 20052,475 shares, last reported balance as of May 27, 2004
Abingworth Management LTDMar 15, 20053,778,522 shares, last reported balance as of May 27, 2005
POLARIS VENTURE MANAGEMENT CO III LLCFeb 24, 20052,018,992 shares, last reported balance as of Feb 2, 2005
Christoph WestphalJun 7, 20042,714,803 shares, last reported balance as of Jun 3, 2004
Christoph WestphalJun 7, 2004100,557 shares, last reported balance as of Jun 3, 2004
ARCH VENTURE FUND V LPJun 1, 2004222,500 shares, last reported balance as of May 27, 2004
Clinton BybeeJun 1, 2004222,500 shares, last reported balance as of May 27, 2004
ARCH V ENTREPRENEURS FUND LPJun 1, 2004222,500 shares, last reported balance as of May 27, 2004
Keith CrandellJun 1, 2004222,500 shares, last reported balance as of May 27, 2004
ARCH VENTURE PARTNERS V LPJun 1, 2004222,500 shares, last reported balance as of May 27, 2004
Robert NelsenJun 1, 2004222,500 shares, last reported balance as of May 27, 2004
Steven LazarusJun 1, 2004222,500 shares, last reported balance as of May 27, 2004
ARCH VENTURE PARTNERS V LLCJun 1, 2004222,500 shares, last reported balance as of May 27, 2004
CHP II LPJun 1, 2004232,500 shares, last reported balance as of May 27, 2004
Thomas UlichMay 27, 2004No balance on record

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